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Skin Lesion Diagnosis using Ensembles, Unscaled Multi-Crop Evaluation and Loss Weighting

Ensemble CNNs with loss weighting and multi-crop evaluation for automated skin lesion diagnosis across seven classes.

Abstract

In this paper we present the methods of our submission to the ISIC 2018 challenge for skin lesion diagnosis (Task 3). The dataset consists of 10000 images with seven image-level classes to be distinguished by an automated algorithm. We employ an ensemble of convolutional neural networks for this task. In particular, we fine-tune pretrained state-of-the-art deep learning models such as Densenet, SENet and ResNeXt. We identify heavy class imbalance as a key problem for this challenge and consider multiple balancing approaches such as loss weighting and balanced batch sampling. Another important feature of our pipeline is the use of a vast amount of unscaled crops for evaluation. Last, we consider meta learning approaches for the final predictions. Our team placed second at the challenge while being the best approach using only publicly available data.

Nils Gessert
Nils Gessert
Research Scientist
Thilo Sentker
Thilo Sentker
Research Scientist
Frederic Madesta
Frederic Madesta
PhD Student
Rüdiger Schmitz
Rüdiger Schmitz
PhD Student
Helge Kniep
Helge Kniep
PhD Student
Ivo Matteo Baltruschat
Ivo Matteo Baltruschat
Co-Founder / Research Scientist

Ivo Matteo Baltruschat studied Information and Electrical Engineering at the University of Applied Sciences, Hamburg between 2010 and 2014. In 2016, he finished his Master of Science in medical engineering science at the Universität zu Lübeck with his thesis on Deep Learning for Advanced Medical Applications. During DAISYlabs, he was a PhD student in the group of Tobias Knopp at the Institute for Biomedical Imaging, Hamburg University of Technology. His research covered the automatic analysis of medical x-ray images using machine learning methods, with a focus on applying deep learning to high-resolution medical x-ray images for computer-aided diagnosis.

René Werner
René Werner
Co-Founder / Head of scientific working group

René Werner co-founded DAISYlabs and led the scientific working group at the University Medical Center Hamburg-Eppendorf, coordinating deep learning research for biomedical image processing across UKE and TUHH.